io.github.pubspro/pharma-mcp
MCP server for ClinicalTrials.gov, PubMed, FDA drug labels, FAERS, and ICH guidelines.
Open source Open in the app JSON README (API)
About
MCP server for ClinicalTrials.gov, PubMed, FDA drug labels, FAERS, and ICH guidelines.
Details
- Kind
- MCP servers
- Topic
- Government & public data
- Publisher
- pubspro
- Origin
- official
- Category
- ferramentas
- Transport
- local
- Version
- 1.0.0
- Last push
- 2026-05-09T11:43:31Z
- Repository state
- ativo
- Added
- 2026-08-29 04:01:15
- Updated
- 2026-08-29 04:01:15
- Origin id
io.github.pubspro/pharma-mcp
README
# pharma-mcp
**MCP server for clinical and pharmaceutical data.**
Gives Claude and any MCP-compatible AI agent direct access to:
- **ClinicalTrials.gov** — search and retrieve trial protocols, endpoints, eligibility criteria
- **PubMed** — literature search with MeSH terms, full abstracts, citation formatting
- **FDA openFDA** — drug labels, approved indications, warnings, boxed warnings
- **FDA FAERS** — adverse event reports with patient demographics and outcomes
- **ICH Guidelines** — structured summaries of E3, E6, E9, M4, Q1A, and more
No API keys required. All data sources are public. Runs locally in under 60 seconds.
---
## Tools
| Tool | Description |
|------|-------------|
| `search_clinical_trials` | Search ClinicalTrials.gov by condition, drug, or sponsor |
| `get_trial_details` | Full protocol details by NCT ID |
| `search_pubmed` | PubMed literature search with MeSH, Boolean, date filters |
| `get_pubmed_abstract` | Full abstract + metadata by PMID |
| `search_fda_drugs` | FDA drug label search — indications, warnings, dosage forms |
| `get_fda_adverse_events` | FAERS adverse event reports by drug and/or reaction |
| `get_ich_guideline` | ICH guideline summaries by code (E3, E6, M4…) or topic |
| `format_citation` | Vancouver, APA, or AMA citation from a PMID |
---
## Quickstart
### Install
```bash
git clone https://github.com/pubspro/pharma-mcp.git
cd pharma-mcp
npm install
```
### Add to Claude Desktop
Edit `~/Library/Application Support/Claude/claude_desktop_config.json` (macOS) or `%APPDATA%\Claude\claude_desktop_config.json` (Windows):
```json
{
"mcpServers": {
"pharma-mcp": {
"command": "node",
"args": ["/absolute/path/to/pharma-mcp/src/index.js"]
}
}
}
```
Restart Claude Desktop. The tools appear automatically.
### Add to Claude Code
```bash
claude mcp add pharma-mcp node /absolute/path/to/pharma-mcp/src/index.js
```
---
## Example prompts
Once connected, ask Claude:
```
Search ClinicalTrials.gov for Phase 3 recruiting trials for non-small cell lung cancer involving osimertinib.
```
```
Find the 10 most recent PubMed papers on GLP-1 receptor agonists and cardiovascular outcomes. Format citations in Vancouver style.
```
```
Get the FDA label for semaglutide — what are the boxed warnings and contraindications?
```
```
What does ICH E3 require for a clinical study report? Which sections are mandatory?
```
```
Pull adverse event reports for dupilumab involving anaphylaxis from FAERS.
```
---
## Use cases
**Medical writers and publications teams**
- Rapid literature gap analysis for advisory boards and manuscripts
- Auto-format reference lists from PubMed searches
- Check ICH E3 requirements mid-draft without switching tabs
**Regulatory affairs**
- Search FDA labels for labeling precedent
- Check FAERS signal for benefit-risk narratives
- Retrieve ICH guideline requirements for CTD modules
**Clinical development**
- Competitive landscape searches across ClinicalTrials.gov
- Identify comparable trial designs and endpoints
**AI agent pipelines**
- Chain pharma-mcp tools with other MCP servers for autonomous regulatory research workflows
---
## Data sources
All data retrieved in real time from official public APIs — no data stored, no API keys required:
- [ClinicalTrials.gov API v2](https://clinicaltrials.gov/data-api/api)
- [NCBI E-utilities (PubMed)](https://www.ncbi.nlm.nih.gov/books/NBK25501/)
- [openFDA API](https://open.fda.gov/apis/)
- [ICH Guidelines](https://www.ich.org/page/guidelines)
---
## Requirements
- Node.js 18+
- npm
---
## Roadmap
- [ ] EMA EPAR search
- [ ] DailyMed full prescribing information
- [ ] GPP4 / ICMJE authorship criteria checker
- [ ] ClinVar genetic variant lookup
PRs and issues welcome.
---
## License
MIT