{
  "markdown": "<!-- mcp-name: io.github.pkotecha-eng/aria-mcp-server -->\n\n# 🧬 ARIA Clinical Research MCP Server\nA standalone MCP server that gives any Claude agent real-time access to biomedical literature and clinical trials — no API keys required.\n[![aria-mcp-server MCP server](https://glama.ai/mcp/servers/pkotecha-eng/aria-mcp-server/badges/score.svg)](https://glama.ai/mcp/servers/pkotecha-eng/aria-mcp-server)\n## Tools\n\n| Tool | Description |\n|------|-------------|\n| `search_pubmed` | Search 35M+ peer-reviewed papers via NCBI E-utilities |\n| `search_clinical_trials` | Search 400K+ trials via ClinicalTrials.gov v2 API |\n| `search_isrctn` | Search UK/European trials via ISRCTN registry |\n\n\n## Prompts\n\n| Prompt | Description |\n|--------|-------------|\n| `clinical-research-brief` | Comprehensive evidence + trial brief for a condition |\n| `adverse-event-analysis` | Structured AE and safety profile for a drug |\n| `trial-eligibility-checker` | Patient eligibility assessment across recruiting trials |\n\n## Resources\n\n| Resource | Description |\n|----------|-------------|\n| `info://aria` | Overview of ARIA capabilities and data sources |\n| `reference://trial-phases` | Phase I–IV definitions and FDA special designations |\n| `reference://high-impact-journals` | Curated high-impact journals by specialty |\n| `reference://fda-databases` | FDA databases for drug, safety, and regulatory research |\n\n## Example queries\n\nOnce connected, ask Claude:\n\n- \"Search PubMed for ketogenic diet pediatric epilepsy outcomes\"\n- \"Find recruiting trials for lung cancer immunotherapy\"\n- \"What does the literature say about veliparib in ovarian cancer, and are there active trials?\"\n- \"Find UK and European trials for pediatric epilepsy via ISRCTN\"\n\n## Quickstart\n\n```bash\npip install aria-mcp-server\naria-mcp-server\n```\n\n## Connect to Claude Desktop\n\nAdd to `~/Library/Application Support/Claude/claude_desktop_config.json`:\n\n```json\n{\n  \"mcpServers\": {\n    \"aria-clinical-research\": {\n      \"command\": \"aria-mcp-server\"\n    }\n  }\n}\n```\n\nRestart Claude Desktop. The server will appear under Settings → Developer → Local MCP Servers.\n\n## Data sources\n\n- **PubMed** — NCBI E-utilities (public API, no key required)\n- **ClinicalTrials.gov** — v2 REST API (public API, no key required)\n- **ISRCTN** — UK/European clinical trials registry (public API, no key required)\n\n## Tech stack\n\n- [FastMCP](https://gofastmcp.com) — MCP server framework\n- Python 3.12+\n\n## Use cases\n\n- Life sciences researchers needing real-time literature access\n- Clinical trial coordinators checking eligibility and recruiting status\n- Drug discovery teams cross-referencing published evidence with active trials\n- Any Claude agent needing grounded biomedical knowledge\n\n\n## Project Structure\n\n```\naria-mcp-server/          ← root, where mcp-publisher runs\n├── aria_mcp_server/      ← Python package\n│   ├── __init__.py\n│   ├── server.py\n│   └── tools.py\n├── server.json           ← MCP registry metadata\n├── pyproject.toml\n├── README.md\n├── LICENSE\n└── glama.json\n```\n\n## Built by\n\nPooja Kotecha · [dinq.me/pkotecha-eng](https://dinq.me/pkotecha-eng)\n",
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