{
  "markdown": "# mcp-hgnc\n\nHGNC (HUGO Gene Nomenclature Committee) MCP.\n\nPart of [Pipeworx](https://pipeworx.io) — an MCP gateway connecting AI agents to 1476+ live data sources.\n\n## Tools\n\n| Tool | Description |\n|------|-------------|\n| `get_gene` | Exact lookup of an approved human gene by its official HGNC symbol — returns the full authoritative record: approved name, locus type, chromosomal location, alias/previous symbols, gene groups, and cross-references (Entrez, Ensembl, UniProt, OMIM, RefSeq, UCSC, CCDS). Use search_genes first if you only have a name fragment or aren't sure of the exact symbol. Keyless. |\n| `search_genes` | Fuzzy search across approved symbols, names, and aliases — e.g. \"breast cancer\", \"p53\", \"tumor protein\". Returns lightweight matches (hgnc_id, symbol, relevance score) ranked by score; call get_gene with a returned symbol for the full record. Keyless. |\n| `resolve_xref` | Reverse-lookup: map an external database id to its canonical HGNC gene. \"What gene is Entrez 672?\" -> BRCA1. Accepts entrez_id, ensembl_gene_id, uniprot_ids, omim_id, refseq_accession, or ucsc_id and returns the same full record as get_gene. Keyless. |\n\n## Quick Start\n\nAdd to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):\n\n```json\n{\n  \"mcpServers\": {\n    \"hgnc\": {\n      \"url\": \"https://gateway.pipeworx.io/hgnc/mcp\"\n    }\n  }\n}\n```\n\n### What this endpoint actually serves\n\n`tools/list` at `https://gateway.pipeworx.io/hgnc/mcp` returns the tools in the table\nabove **plus the shared Pipeworx meta-tools** — `ask_pipeworx`,\n`discover_tools`, `search_within`, `remember`/`recall` and the rest of the\ngateway-wide set. So the tool count you see is larger than this table: a\nsingle-pack endpoint currently lists roughly 30 shared tools alongside the\npack's own. The connection's `initialize` response states its exact scope, and\nis the authoritative answer for a given day.\n\nThis is deliberate, not multiplexing by accident. The meta-tools are what let a\nscoped connection answer a question this pack does not cover — via\n`ask_pipeworx`, which routes across the whole catalog — without you adding a\nsecond MCP server. There is currently no way to mount a pack endpoint without\nthem; if the extra schemas cost you more context than the routing is worth,\nconnect to the full gateway once rather than to several pack endpoints.\n\nOr connect to the full Pipeworx gateway to get every pack's tools listed\ndirectly, instead of just this one's:\n\n```json\n{\n  \"mcpServers\": {\n    \"pipeworx\": {\n      \"url\": \"https://gateway.pipeworx.io/mcp\"\n    }\n  }\n}\n```\n\nBoth URLs reach the same gateway and the same 1476+ data sources. The\nonly difference is which pack's tools are listed **directly**; `ask_pipeworx`\nreaches all of them from either one.\n\n## Using with ask_pipeworx\n\nInstead of calling tools directly, you can ask questions in plain English —\nthis works on the pack endpoint above as well as on the full gateway:\n\n```\nask_pipeworx({ question: \"your question about Hgnc data\" })\n```\n\nThe gateway picks the right tool and fills the arguments automatically.\n\n## More\n\n- [Docs and guides](https://pipeworx.io/docs)\n- [pipeworx.io](https://pipeworx.io)\n\n## License\n\nMIT\n",
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  "repo_slug": "pipeworx-io/mcp-hgnc",
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}